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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC23IP
All Species:
3.33
Human Site:
S258
Identified Species:
7.33
UniProt:
Q9Y6Y8
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6Y8
NP_009121.1
1000
111076
S258
A
P
S
V
Q
V
P
S
P
F
L
L
Q
N
Q
Chimpanzee
Pan troglodytes
XP_508076
1000
111144
P258
A
P
S
V
Q
V
P
P
P
F
L
L
Q
N
Q
Rhesus Macaque
Macaca mulatta
XP_001100615
1000
110977
P258
A
P
S
V
Q
V
P
P
P
F
L
L
Q
N
Q
Dog
Lupus familis
XP_535037
1003
111786
V258
A
R
P
A
G
P
S
V
H
A
P
P
F
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6NZC7
998
110762
F256
L
V
Q
G
P
S
P
F
V
L
Q
N
Q
Y
E
Rat
Rattus norvegicus
NP_001128331
999
110925
P256
P
L
V
Q
G
P
S
P
F
V
L
Q
N
Q
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515025
1007
112022
S265
S
T
P
L
I
Q
A
S
P
L
L
L
H
S
H
Chicken
Gallus gallus
XP_424389
690
77700
L47
T
G
G
R
E
R
W
L
P
F
S
T
Q
D
S
Frog
Xenopus laevis
NP_001087410
1007
112007
P257
A
G
P
S
V
P
V
P
P
P
Y
L
P
N
L
Zebra Danio
Brachydanio rerio
NP_001070847
977
109367
Y256
P
V
Q
P
H
W
F
Y
C
K
Q
V
E
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796242
926
103546
V262
K
E
M
E
K
R
S
V
W
V
P
F
S
I
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
98.1
91.3
N.A.
86.3
88
N.A.
79.2
39.7
66.3
63.5
N.A.
N.A.
N.A.
N.A.
42.7
Protein Similarity:
100
99.3
98.8
93.4
N.A.
91.4
92.6
N.A.
86.3
51.5
76.4
74.9
N.A.
N.A.
N.A.
N.A.
56
P-Site Identity:
100
93.3
93.3
6.6
N.A.
13.3
6.6
N.A.
26.6
20
26.6
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
93.3
93.3
6.6
N.A.
20
6.6
N.A.
46.6
33.3
26.6
26.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
46
0
0
10
0
0
10
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
0
10
0
10
10
0
0
0
0
0
0
0
10
0
10
% E
% Phe:
0
0
0
0
0
0
10
10
10
37
0
10
10
0
0
% F
% Gly:
0
19
10
10
19
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
10
0
0
0
10
0
0
0
10
0
10
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
10
% I
% Lys:
10
0
0
0
10
0
0
0
0
10
0
0
0
0
10
% K
% Leu:
10
10
0
10
0
0
0
10
0
19
46
46
0
10
19
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
10
37
0
% N
% Pro:
19
28
28
10
10
28
37
37
55
10
19
10
10
0
0
% P
% Gln:
0
0
19
10
28
10
0
0
0
0
19
10
46
10
28
% Q
% Arg:
0
10
0
10
0
19
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
28
10
0
10
28
19
0
0
10
0
10
19
10
% S
% Thr:
10
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% T
% Val:
0
19
10
28
10
28
10
19
10
19
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
10
10
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
10
0
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _